Bottling and packaging of sterile medical products. Machine after validation of sterile liquids

Pharmaceutical Production

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Pharmaceutical Production

Country
Sector
Most major industry classification systems use sources of revenue as their basis for classifying companies into specific sectors, subsectors and industries. In order to group like companies based on their sustainability-related risks and opportunities, SASB created the Sustainable Industry Classification System® (SICS®) and the classification of sectors, subsectors and industries in the SDG Investor Platform is based on SICS.
Health Care
Sub Sector
Most major industry classification systems use sources of revenue as their basis for classifying companies into specific sectors, subsectors and industries. In order to group like companies based on their sustainability-related risks and opportunities, SASB created the Sustainable Industry Classification System® (SICS®) and the classification of sectors, subsectors and industries in the SDG Investor Platform is based on SICS.
Biotechnology and Pharmaceuticals
Indicative Return
Describes the rate of growth an investment is expected to generate within the IOA. The indicative return is identified for the IOA by establishing its Internal Rate of Return (IRR), Return of Investment (ROI) or Gross Profit Margin (GPM).
5% - 10% (in IRR)
Investment Timeframe
Describes the time period in which the IOA will pay-back the invested resources. The estimate is based on asset expected lifetime as the IOA will start generating accumulated positive cash-flows.
Medium Term (5–10 years)
Market Size
Describes the value of potential addressable market of the IOA. The market size is identified for the IOA by establishing the value in USD, identifying the Compound Annual Growth Rate (CAGR) or providing a numeric unit critical to the IOA.
USD 100 million - USD 1 billion
Average Ticket Size (USD)
Describes the USD amount for a typical investment required in the IOA.
> USD 10 million
Direct Impact
Describes the primary SDG(s) the IOA addresses.
Good health and well-being (SDG 3) Industry, Innovation and Infrastructure (SDG 9) Partnerships For the Goals (SDG 17)
Indirect Impact
Describes the secondary SDG(s) the IOA addresses.
Decent Work and Economic Growth (SDG 8) Quality Education (SDG 4)

Business Model Description

Manufacture pharmaceutical products in solid, semi-solid, liquid and other dosage forms as well as powders, aerosols and ophthalmic eye / ear / nasal drops to serve national and regional markets, leveraging on the country's access to African Continental Free Trade Area (AfCFTA) and preferential trade areas in the region, including Southern African Development Community (SADC) and Common Market for Eastern and Southern Africa (COMESA).

Expected Impact

Enhance affordability of and access to pharmaceutical products, and increase competitiveness and innovation of Mauritius' healthcare industry through technological developments.

How is this information gathered?

Investment opportunities with potential to contribute to sustainable development are based on country-level SDG Investor Maps.

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Country & Regions

Explore the country and target locations of the investment opportunity.
Country
Region
  • Mauritius: Grand Port
  • Mauritius: Plaines Wilhems
  • Mauritius: Port Louis
  • Mauritius: Rivière du Rempart
Learn more

Sector Classification

Situate the investment opportunity within sustainability focused sector, subsector and industry classifications.
Sector

Health Care

Development need
Prevalence of noncommunicable diseases (NCDs), aging population with increasing needs and ensuring well-being of non-nationals living, working or visiting Mauritius urge improvements in country's well-developed healthcare system. Cost and supply chain vulnerabilities arise from dependency on medical equipment and pharmaceutical imports and specific treatments abroad (1, 2).

Policy priority
Mauritius aims to sustain provision of free healthcare services to an aging population with higher specialized treatment needs and quality expectations, through Five-Year Health Sector Strategic Plan 2020-2024 (3). Government agenda foresees positioning Mauritius as a medical hub, improving the independence of the sector and enhancing local production to serve wider Africa market.

Gender inequalities and marginalization issues
Serving Rodrigues and Agaléga and enhancing the well-being of the population in remote islands are strategic actions for the government (3). Self-perceived health is higher among men as only 67% of women rated their health status as ‘good or very good’ compared to 76% of men (4).

Investment opportunities introduction
Economic Development Board (EDB) Mauritius directs the efforts in situating the country as a medical hub (5). Government offers free healthcare services and allocate some MUR 14.5 billion (USD 300 million) to health budget (6). Various incentives, Extensive Exclusive Economic Zone (EEZ) and untapped marine resources stand as prospects for the sector (7).

Key bottlenecks introduction
Growing burden of noncommunicable diseases (NCDs) and high reliance on medical equipment and pharmaceutical imports are the key challenges. Certain specialized treatment cannot be undertaken in Mauritius and patients must be sent abroad. Absence of a central computerized data repository for health and lack of strong regulation limit the development of the sector (3).

Sub Sector

Biotechnology and Pharmaceuticals

Development need
In Sub-Saharan Africa, imports represent 70-90% of drug consumption in most countries, and more than 90% in import-dependent Mauritius. Diversification and innovation of economy around high-value products such as pharmaceuticals is critical for fragile economies of Small Island Developing States (SIDS), including Mauritius, as demonstrated by the COVID-19 crisis (9).

Policy priority
In Mauritius, value of pharmaceutical imports constitutes around 20% of the total healthcare expenditure (10). In order to develop local production capacity and target the entire Sub-Saharan Africa region, pharmaceutical production is incentivized, and Mauritius Institute of Biotechnology and a dedicated Pharmaceutical and Life Sciences Business Park have been established (11).

Gender inequalities and marginalization issues
Local pharmaceutical production will increase decent job opportunities for women and sustain access to medicines, lack of which is mostly detrimental to well-being of the poor, women and especially children (12).

Investment opportunities introduction
Land availability in Pharmaceutical and Life Sciences Business Park in Rose Belle, fiscal and financial incentives including refund on air and basic freight costs, and preferential access to Southern African Development Community (SADC) and Common Market for Eastern and Southern Africa (COMESA) support the development of pharmaceutical production (13, 14).

Key bottlenecks introduction
Strong regulation and expertise around certification, licensing schemes and abiding by guidelines and inspection are exigencies of operational success. Raw materials, bulk chemicals for production, packaging materials, machinery, and active pharmaceutical ingredients (API) should be imported. Curriculum shall be adapted to industry needs in relevant professions (15).

Industry

Biotechnology and Pharmaceuticals

Pipeline Opportunity

Discover the investment opportunity and its corresponding business model.
Investment Opportunity Area

Pharmaceutical Production

Business Model

Manufacture pharmaceutical products in solid, semi-solid, liquid and other dosage forms as well as powders, aerosols and ophthalmic eye / ear / nasal drops to serve national and regional markets, leveraging on the country's access to African Continental Free Trade Area (AfCFTA) and preferential trade areas in the region, including Southern African Development Community (SADC) and Common Market for Eastern and Southern Africa (COMESA).

Business Case

Learn about the investment opportunity’s business metrics and market risks.

Market Size and Environment

Market Size (USD)
Describes the value in USD of a potential addressable market of the IOA.

USD 100 million - USD 1 billion

Critical IOA Unit
Describes a complementary market sizing measure exemplifying the opportunities with the IOA.

USD 150 million import value of pharmaceuticals in 2020

​Mauritius' pharmaceuticals market size increased from USD 147 million in 2020 to USD 155 million in 2021, according to estimates. Total local production is only USD 3 million in the same year (13).

In 2020, the import value for pharmaceuticals in Mauritius was around USD 150 million, whereas re-exports and local production were around USD 24 million and USD 3 million, respectively (11, 13).

Indicative Return

IRR
Describes an expected annual rate of growth of the IOA investment.

5% - 10%

According to consultation with the investment promotion agency, an IRR of 8-9% is expected for pharmaceutical production investments (22).

The consolidated financial statements of Ajanta Pharma (Mauritius) Ltd., and its subsidiary Ajanta Pharma Mauritius (International) Ltd., for the financial year 2020-2021 give a total income of MUR 1.5 billion (USD 38 million) and a gross profit margin of 35% (16).

Investment Timeframe

Timeframe
Describes the time period in which the IOA will pay-back the invested resources. The estimate is based on asset expected lifetime as the IOA will start generating accumulated positive cash-flows.

Medium Term (5–10 years)

A pharmaceutical production unit project is expected to materialize within two years, while the business will generate returns in five to seven years provided that final products are ready to be sold in the export market, meeting the international requirements for manufacturing units (15).

Ticket Size

Average Ticket Size (USD)
Describes the USD amount for a typical investment required in the IOA.

> USD 10 million

Market Risks & Scale Obstacles

Business - Supply Chain Constraints

Because of geographic isolation and dependent supply chains, Mauritius imports most of the products needed for pharmaceutical production, exports waste from biopharmaceuticals for destruction due to lack of adequate infrastructure and requires foreign workforce due to skills gap in related fields.

Capital - CapEx Intensive

Pharmaceutical production in Mauritius entails high machinery costs and imports of raw materials and intermediate goods. Aegle Pharma's ongoing project for production of pharmaceutical generics is valued at USD 10 million (11).

Market - Highly Regulated

Companies engaged in pharmaceutical production have to abide by certain international guidelines, inspection and certification schemes, exemplified by World Health Organization Good Manufacturing Practices (WHO GMP) and The Pharmaceutical Inspection Co-operation Scheme (PIC/S).

Impact Case

Read about impact metrics and social and environmental risks of the investment opportunity.

Sustainable Development Need

Ageing population and high prevalence of non-communicable diseases (NCDs), including cardiovascular diseases, diabetes, hypertension and cancer increase the need for specialized and quality treatment as well as medication (1).

Mauritius' high reliance on medical equipment and pharmaceutical imports lead to high costs and vulnerabilities in case of a supply chain disruptions, as observed during the COVID-19 pandemic (12).

Mauritius has a skills gap in certain professions that the pharmaceutical production industry and linked sectors require, including industrial pharmacist, toxicologist, microbiologist, nurse, which makes the country dependent on the foreign workforce (15).

Gender & Marginalisation

In case of a supply chain disruption, leading to higher prices, vulnerable and isolated groups in the society are exposed to higher risks of failing to access medication.

Expected Development Outcome

Pharmaceutical production decreases the dependency on imports, lowers drug costs and streamline the pharmaceutical value chain, ultimately benefitting the population's access to affordable medication.

The development of pharmaceutical production contributes to high margin goods exports as well as advances the innovation and research and development (R&D) ecosystem in Mauritius.

Pharmaceutical production creates a conducive environment to support industry-academy collaboration in provision of quality technical, vocational and tertiary education in relevant fields where country lacks skilled personnel and depends on foreign labor force.

Gender & Marginalisation

Pharmaceutical production in Mauritius, targeting the export and wider Sub-Saharan African market, benefits the poor, women and children who lack access to medicine due to acute shortages in the region.

Primary SDGs addressed

Good health and well-being (SDG 3)
3 - Good Health and Well-Being

3.4.1 Mortality rate attributed to cardiovascular disease, cancer, diabetes or chronic respiratory disease

3.8.2 Proportion of population with large household expenditures on health as a share of total household expenditure or income

Current Value

In 2019, 23.2% for both sexes (18.1% for female and 28.3% for male), with Diabetes Mellitus being the main cause (22%) of mortality due to noncommunicable diseases (NCDs), which account for 80% of the disease burden and 85% of mortality in the country (3, 17).

Estimated at 1.7% in 2012; in 2014, per capita out-of-pocket spending on health was around MUR 8,568.540 (USD 275) in Mauritius (17, 19).

Target Value

National 2024 targets address risk factors of noncommunicable diseases (NCDs) that include increasing prevalence of physical activity among the population from 23.7% in 2019 to 35.1%, to achieve the global target, 9.3% rate of probability of dying between the ages of 30 and 70 years from cardiovascular diseases, cancer, diabetes or chronic respiratory diseases, in the long term (3, 18).

Mauritius government targets, by 2024, less than 3% of the population will have endured catastrophic health expenditures (3).

Industry, Innovation and Infrastructure (SDG 9)
9 - Industry, Innovation and Infrastructure

9.b.1 Proportion of medium and high-tech industry value added in total value added

9.2.1 Manufacturing value added as a proportion of GDP and per capita

Current Value

4.65% in 2018, according to modelled data (17).

Manufacturing value added as a proportion of GDP is 10.4% and per capita is USD 927 in 2020, according to modelled data (17).

Target Value

Manufacturing sector is expected to grow at a CAGR of 6.79 % between 2018 and 2030, including pharmaceuticals productions and medical device manufacturing as subsectors (20).

Voluntary National Review (VNR) Report of Mauritius 2019 indicates the target of an annual growth rate of at least 3% in the manufacturing sector over the following three years. Ministry of Industrial Development, SMEs and Cooperatives and United Nations Conference on Trade and Development (UNCTAD) published a document targeting industrial policy and key sectors between 2020-2025 (1, 20).

Partnerships For the Goals (SDG 17)
17 - Partnerships For the Goals

17.3.1 Foreign direct investment, official development assistance and South-South cooperation as a proportion of gross national income

Current Value

Total foreign direct investment as a proportion of gross national income (proxy indicator) is 4.2% in 2019 (28).

Target Value

N/A

Secondary SDGs addressed

Decent Work and Economic Growth (SDG 8)
8 - Decent Work and Economic Growth
Quality Education (SDG 4)
4 - Quality Education

Directly impacted stakeholders

People

Patients have improved access to affordable medication and decreased out-of-pocket (OOP) spending on health.

Planet

Environment benefits form improved biopharmaceutical waste management.

Corporates

Pharmaceuticals manufacturers, material/ingredient suppliers and distributors, medical logistics and warehousing service providers, pre-clinical and clinical contract research organizations (CRO).

Public sector

The Government benefits from improved regulatory capacity, balance of trade, extended industrial value base and decreased pressure on health budget benefits the public sector.

Indirectly impacted stakeholders

People

Medium to high skilled workers obtain new employment, and training opportunities to advance skills development.

Gender inequality and/or marginalization

Women, the poor and children benefit from reduced risks of losing access to basic medication thanks to local production.

Planet

Thanks to the local pharmaceuticals production, transportation needs, which harms the environment, are reduced.

Corporates

Input providers within the agriculture and blue economy sectors.

Outcome Risks

The increasing medical and clinical waste from pharmaceutical production, if not managed and treated sufficiently, may negatively impact people and the planet.

Impact Risks

Dependency on raw materials and active pharmaceutical ingredients (APIs) imports may limit the impact in case of failing to achieve the production capacity required to be cost competitive (8).

Although total job creation by pharmaceutical production will be low, it requires a highly-skilled workforce, which may be chosen from foreign candidates and hence limiting the positive impact in the country.

Impact Classification

C—Contribute to Solutions

What

Pharmaceutical production ensures availability of affordable medication, improves the pharmaceutical value chain to benefit innovation and industry, and generates few but high skilled jobs.

Who

Pharmaceutical manufacturers, clinical researchers, patients and health professionals, as well as government through decreased spending, benefit from pharmaceutical production.

Risk

The affordability of pharmaceuticals and a potential influx of foreign employees due to a skills mismatch between the domestic labor market and the pharmaceutical sector may affect impact.

Contribution

Pharmaceutical production contributes to development of a sizeable local industry and will pioneer other high value industries, including vaccine production and biotechnology.

How Much

Pharmaceutical production will contribute to a sizeable industry in Sub-Saharan Africa, where the market is valued at USD 14 billion and 70-90% of consumed drugs come from imports (8).

Impact Thesis

Enhance affordability of and access to pharmaceutical products, and increase competitiveness and innovation of Mauritius' healthcare industry through technological developments.

Enabling Environment

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Policy Environment

Health Sector Strategic Plan 2020-2024, 2020: Provides a coherent framework that unveils concrete strategies and interventions to address major health challenges in the country and peoples’ expectations for an enhanced quality of services across their lifespan (3).

SADC Pharmaceutical Business Plan, 2007-2013: Targets to guarantee the availability of vital medications, including traditional African medicines, to minimize illness burden in the member nations, including Mauritius (23).

Financial Environment

Financial incentives: Export Credit Guarantee Insurance Scheme provides an Economic Development Board (EDB) subsidy on the cost of Credit Guarantee Insurance Premium to eligible companies subscribing for Credit Insurance Cover for their direct exports worldwide, including for pharmaceuticals.

Fiscal incentives: More than ten incentives are applicable to pharmaceutical production, including 8-year corporate tax holiday, full tax credit on the costs of acquisition of patents, no registration duty or land transfer tax on purchase or lease of land or building (11).

Other incentives: Premium investor certificate is granted to all companies engaged in the manufacture of pharmaceuticals. 60% of air freight cost for export to Africa (including Madagascar), Australia, Canada, Europe, Japan, Middle East Countries and USA is subject to refund (until June 2022) (11).

Regulatory Environment

Pharmacy Act, 1983: Regulates all aspects of the pharmaceutical manufacturing value chain (11).

Clinical Trials Act, 2011: Regulates the conduct of clinical trials for the purpose of discovering or verifying the effects of investigational medicinal products (11).

Animal Welfare Act (Experiment on Animals), 2017: Regulates animal testing in Mauritius and is modelled as per international guidelines (11).

Environment Protection Act, 2002: Addresses environmental protection and management issues and enforces environmental norms, with regard to waste discharge and emissions within pharmaceutical manufacturing facilities (11).

Dangerous Chemicals Control Act, 2004 : Regulates the classification, labelling and sale of dangerous chemicals, among others, and establishes the Dangerous Chemicals Advisory Council and the Dangerous Chemicals Control Board (21).

Marketplace Participants

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Private Sector

Ajanta Pharma (Mauritius) Ltd., Xylomed Pharmaceuticals, Aegle Pharma, Cap Research Ltd., Centre International de Développement Pharmaceutique (CIDP), Clinear Research Ltd., Centre d’Etudes Cliniques Ltee., Insight Research, Axonova Ltd., Delonix Laboratories.

Government

Ministry of Health and Wellness, Pharmacy Board, Ministry of Agro Industry and Food Security, Ministry of Environment Solid Waste Management and Climate Change, Landscope (Mauritius) Ltd.

Multilaterals

World Health Organization (WHO), United Nations Development Programme (UNDP), Southern African Development Community (SADC), Common Market for Eastern and Southern Africa (COMESA).

Non-Profit

University of Mauritius, JSS Academy, Sir Seewoosagur Ramgoolam Medical College.

Target Locations

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country static map
semi-urban

Mauritius: Grand Port

Government of Mauritius established a dedicated Pharmaceutical and Life Sciences Business Park, through its property development arm Landscope Mauritius, in Rose Belle, Grand Port. All activities related to biotechnology and pharmaceuticals are envisioned to be located in this zone (24).
urban

Mauritius: Plaines Wilhems

Key Contract Research Organization (CRO) companies that conduct clinical trials in the country are situated around BioPark Mauritius, in Plaines Wilhems district. These companies may partner with companies from emerging pharmaceutical and biotechnology industries (7, 25).
urban

Mauritius: Port Louis

Pharmaceutical producers may structure their business operations around Port Louis district, which is the key maritime outlet and administrative center of the country as well as home to key pharmaceutical wholesalers (27).
semi-urban

Mauritius: Rivière du Rempart

Mauritius currently hosts a single pharmaceutical manufacturer that is operating from Goodlands, Rivière du Rempart (26).

References

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